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|Matthew Broderick||Richard Feynman|
|Patricia Arquette||Arline Greenbaum|
|Peter Riegert||Mel Feynman|
|Jeffrey Force||Young Richard|
|David Drew Gallagher||Harold|
|Raffi Di Blasio||Robert|
|James Hong||Abacus Adder|
|Melissa DeLizia||Young Joan|
|Peter Michael Goetz||Dr. Gell-Mann|
|Joyce Van Patten|
The film follows the book What Do You Care What Other People Think? fairly closely in terms of the stories told.The film starts in 1924 with Richard and his father Melville walking through the woods where Melville shows his scientific inspiration for Richard. In 1934, Richard & Arline are in high school and their romantic relationship starts. The story then jumps to his college years and Arline getting sick with lymphatic tuberculosis. It continues to his move west to Los Alamos National Laboratory in Los Alamos, New Mexico, where Arline follows him later to a hospital in Albuquerque, New Mexico, where she dies. The film ends with Feynman crying at the sight of the red dress Arline had pointed out.